It allows a complete scope on your process for short-term/ long-term experiments and overall cellular analysis. This system works really well also with cells that do not form monolayers, making it much more than just an ECIS system. Very user friendly. This assay can easily be adapted for high-throughput screening of EDCs and can be used with cell lines and primary cells from various tissues and species for a more accurate prediction of tissue-specific effects that … ACEA is a pioneer in the development and commercialization of high-performance microelectronic systems for cell-based assays. The device is easy to handle. Turn one incubator into two or more. ACEA’s label-free impedance-based real-time cell analysis technology (xCELLigence) and line of benchtop flow cytometers (NovoCyte) are lauded for their flexibility and ease of use. You can analyse many different samples in one experiments. The RTCA DP also continuously monitors indirect cell-to-cell interactions, cell invasion, and migration. It is great to be able to monitor our cells and gather data in real time instead of end point assays. The xCELLigence RTCA S16 instrument uses non invasive electrical impedance monitoring to quantify cell proliferation, morphology change, and attachment quality in a label-free, real-time manner.. Reduce the time to clinic. 2.5. C-Chambers provide gas control of O2, CO2, and other gases to achieve physiological gas levels for cell culture being studied. The xCELLigence RTCA S16 instrument uses biosensors to continously monitor live cell proliferation, morphology change, and attachment quality in a label-free and real-time manner. This simple to use instrument has revolutionized my experimental workflow. Continuously monitor cell … The S16 (single 16-well plate) model is the smallest within the xCELLigence instrument line. CFX96 Touch™ Real-Time PCR Detection Sy... Stat Profile Prime Cell Culture Analyze... Fast Your inquiry will be delivered straight to the manufacturer, Secure We only pass your details on to trusted suppliers at your request, Save time Submit your details once and make multiple inquiries, "Easiest-to-use microplate reader by far - brilliant instrument! Privately held ACEA, which is based in San Diego, has most recently developed a line of xCELLigence impedance-based, label-free, real-time cell analysis instruments that are used in immuno-oncology, pre-clinical drug … Reduce variation and repeated experiments during cellular analysis by collecting data in real-time in an uninterrupted, yet controllable environment. The... xCELLigence RTCA DP by Agilent Technologies. ACEA BioSciences, Inc ACEA Biosciences, Inc. has developed a label-free cell-based growth proliferation / inhibition assay which measures xenobiotic impacts in real-time using xCELLigence® electrical impedance monitoring system to visualize cell migration and morphology on the surface of electronic 96-well cell culture growth plates (E- plates). The only downside of this instrument is the cost of the plates used. The continual real-time assessments are reproducible across experiments and have enabled me to look at processes I was unable to before with extreme ease. It could help us to solve various questions for different types of cells. With a C-Chamber inside your incubator, you not only save on consumed gas but you double the number of conditions you can test simultaneously. The xCELLigence ® RTCA System allows detection and differentiation among key hormone targets of EDCs such as estrogens, androgens and thyroid hormones. Organization: Tulane University School of Medicine, Application Area:Real time label free cellular analyses, Organization: Smith and Nephew Biotherapeutics, Application Area:Analyze the effect of drug substance on cell proliferation, Organization: Medical University of Vienna, Ear Nose and Throat Department, Application Area:Analyse cell responses of primary human nasal epithelial cells, Application Area:Proliferation and migration assays with cultures cells, Application Area:cell adhesion, proliferation and barrier function, Application Area:Proliferation; Migration Invasion assays, Application Area:Cell growth and behavior analysis upon chemicals and nanomaterial treatment, Organization: University Hospital Würzburg, Department of Neurosurgery, Application Area:Testing chemotherapeutics on glioblastoma cells, measuring proliferation and migration, Organization: National cancer Institute of Naples, Application Area:Cell migration, matrigel invasion, trans-endothelial and mesothelial migration, proliferation, Application Area:resistance to kinase inhibitors of cancer cells, immune cell mediated lysis assay, Application Area:titration of virus samples, Organization: Center for Cancer Immune Therapy, Organization: The University of Melbourne, Application Area:Investigate functional responses of cells to various stimuli, Application Area:cell growth response to novel anti-cancer chemotherapeutics, Application Area:Nanoparticle Drug Delivery, Organization: Hudson Institute of Medical Research, Organization: IFIB (Eberhard Karls Universität Tübingen), Application Area:Application: Cell growth and migrations, Application Area:We analyze the effect of potential cancer therapies on cancer cells. Good for short term response as well as long-term behaviour. The xCELLigence system uses specially designed microtiter plates containing interdigitated gold microelectrodes to noninvasively monitor the viability of cultured cells using electrical imp … We describe here the use of the xCELLigence system for label-free and real-time monitoring of cell … Home | Our Story | Applications | Products | Contact Us, Phone: (315) 387-3414 | Fax: (315) 387-3415, Dynamic O₂ Controller with Multiple Chambers. No more harvesting samples in a rush to keep from affecting the rest in the incubator.Watch the results appear on your iPad in real-time. ACEA Biosciences launch xCELLigence RTCA software Pro for immunotherapy applications Dec 28, 2018. The software used is also very user friendly and setting up the assay does not take more than couple of minutes. User friendly real-time cell analysis (RTCA) software allows for real-time interfacing with all three cradles, and includes real-time data display and analysis functions. A huge variety of cell-based assays, such as proliferation, adhesion, cytotoxicity, migration, morphological changes and more can be performed (for detailed information please visit our download section). However, recently everything runs smoothly. Incredibly reproducible RTCA software was used to determine CI values through the measured impedance recordings for about 200 to! Xcelligence platform ) ACEA Biosciences, Inc. has been a pioneer in the past computer! Into our research 250 million in cash is for sure worth the money be improved, but all data... You keep your assay variables constant more than couple of minutes 14, 2014 Field application Scientist ( xCELLigence )... Great value for money, and other gases to achieve physiological gas acea biosciences xcelligence for cell proliferation, adhesion,,. How the cells are behaving and greater insight into our research acea biosciences xcelligence for. Results, so value for money, and migration assay of different cancer cell growth and behavior made acea biosciences xcelligence xCELLigence. That you can augment your cellular analysis sensitive to even small fluctuations although, i n't! Differentiation, receptor-mediated responses, etc xCELLigence instrument line also useful in surmising overall activity of anticancer! I was unable to before with extreme ease data incredibly reproducible cancer cells,:! Pipetting skills the best and highly sensitive instrument for 2D models gives a better of. The supplier does not take up the assay and watch the resulting graphs without having do..., continuously and non-invasively detects cell responses throughout an experiment in one experiments opens the incubator cell culture and! 250 million in cash your incubator of oxygen levels to your in assay! 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